I found this on my hard drive and I just can't remember where I first found it. Well, irrespective of whence it came, I think it's pretty good.
In 1879 preeminent American chemist Ira Remsen made the greatest discovery of his career by accident. When he ate rolls at dinner after a long day in the lab researching coal derivatives, he noticed that the rolls tasted initially sweet but then bitter. Since his wife tasted nothing strange about the rolls, Remsen tasted his fingers and noticed that the bitter taste was probably from one the chemicals in his lab. The next day at his lab tasted the chemicals that he had been working with the previous day and discovered that it was the oxidation of o-toluenesulfonamide he had tasted the previous evening. He named the substance “saccharin.”
Remsen was well known as a chemist who was truly entertained by what he found in his chemistry lab. Here's an sample of his writing that shows what a neat guy he must have been:
While reading a textbook of chemistry I came upon the statement, "nitric acid acts upon copper." I was getting tired of reading such absurd stuff and I was determined to see what this meant. Copper was more or less familiar to me, for copper cents were then in use. I had seen a bottle marked nitric acid on a table in the doctor's office where I was then "doing time." I did not know its peculiarities, but the spirit of adventure was upon me. Having nitric acid and copper, I had only to learn what the words "act upon" meant. The statement "nitric acid acts upon copper" would be more than mere words.
All was still. In the interest of knowledge I was even willing to sacrifice one of the few copper cents then in my possession. I put one of them on the table, opened the bottle marked nitric acid, poured some of the liquid on the copper and prepared to make an observation. But what was this wonderful thing which I beheld? The cent was already changed and it was no small change either. A green-blue liquid foamed and fumed over the cent and over the table. The air in the neighborhood of the performance became colored dark red. A great colored cloud arose. This was disagreeable and suffocating. How should I stop this?
I tried to get rid of the objectionable mess by picking it up and throwing it out of the window. I learned another fact. Nitric acid not only acts upon copper, but it acts upon fingers. The pain led to another unpremeditated experiment. I drew my fingers across my trousers and another fact was discovered. Nitric acid acts upon trousers.
Getman, F.H. "The Life of Ira Remsem"; Journal of Chemical Education: Easton, Pennsylvania, 1940; pp9-10